Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays a pivotal role in synaptic plasticity. It is a dodecameric serine/threonine kinase that has been highly conserved across metazoans for over a million years. Despite the extensive knowledge of the mechanisms underlying CaMKII activation, it...

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Detalles Bibliográficos
Autores principales: Tsujioka, Shotaro, Sumino, Ayumi, Nagasawa, Yutaro, Sumikama, Takashi, Flechsig, Holger, Puppulin, Leonardo, Tomita, Takuya, Baba, Yudai, Kakuta, Takahiro, Ogoshi, Tomoki, Umeda, Kenichi, Kodera, Noriyuki, Murakoshi, Hideji, Shibata, Mikihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313165/
https://www.ncbi.nlm.nih.gov/pubmed/37390213
http://dx.doi.org/10.1126/sciadv.adh1069

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