A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition

Triple-negative breast cancer (TNBC), a highly metastatic breast cancer subtype, has limited treatment options. While a small number of patients attain clinical benefit with single-agent checkpoint inhibitors, identifying these patients before the therapy remains challenging. Here, we developed a tr...

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Detalles Bibliográficos
Autores principales: Arulraj, Theinmozhi, Wang, Hanwen, Emens, Leisha A., Santa-Maria, Cesar A., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313177/
https://www.ncbi.nlm.nih.gov/pubmed/37390206
http://dx.doi.org/10.1126/sciadv.adg0289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313177/
https://www.ncbi.nlm.nih.gov/pubmed/37390206
http://dx.doi.org/10.1126/sciadv.adg0289

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