Human endogenous retrovirus K contributes to a stem cell niche in glioblastoma

Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8% of the human genome. Although normally silenced, the most recently integrated provirus HERV-K (HML-2) can be reactivated in certain cancers. Here, we report pathological expression of HML-2 in malignant glioma...

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Detalles Bibliográficos
Autores principales: Shah, Ashish H., Rivas, Sarah R., Doucet-O’Hare, Tara T., Govindarajan, Vaidya, DeMarino, Catherine, Wang, Tongguang, Ampie, Leonel, Zhang, Yong, Banasavadi-Siddegowda, Yeshavanth Kumar, Walbridge, Stuart, Maric, Dragan, Garcia-Montojo, Marta, Suter, Robert K., Lee, Myoung-Hwa, Zaghloul, Kareem A., Steiner, Joseph, Elkahloun, Abdel G., Chandar, Jay, Seetharam, Deepa, Desgraves, Jelisah, Li, Wenxue, Johnson, Kory, Ivan, Michael E., Komotar, Ricardo J., Gilbert, Mark R., Heiss, John D., Nath, Avindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313366/
https://www.ncbi.nlm.nih.gov/pubmed/37395282
http://dx.doi.org/10.1172/JCI167929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313366/
https://www.ncbi.nlm.nih.gov/pubmed/37395282
http://dx.doi.org/10.1172/JCI167929

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