Cargando…

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists

Neurokinin 3 receptor (NK3R) is a tachykinin receptor essential for the hypothalamic-pituitary-gonadal axis. The endogenous peptide agonist neurokinin B (NKB) preferentially activates NK3R, while substance P (SP) binds preferentially to NK1R. In addition, the SP analogue senktide more potently activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Wenjing, Yang, Fan, Zhang, Huanhuan, Yuan, Qingning, Ling, Shenglong, Wang, Yuanxia, Lv, Pei, Li, Zelin, Luo, Yifan, Liu, Dongsheng, Yin, Wanchao, Shi, Pan, Xu, H. Eric, Tian, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313662/
https://www.ncbi.nlm.nih.gov/pubmed/37391393
http://dx.doi.org/10.1038/s41421-023-00564-w