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MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations

Cryo electron tomography (cryo-ET) allows observing macromolecular complexes in their native environment. The common routine of subtomogram averaging (STA) allows obtaining the three-dimensional (3D) structure of abundant macromolecular complexes, and can be coupled with discrete classification to r...

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Detalles Bibliográficos
Autores principales: Vuillemot, Rémi, Rouiller, Isabelle, Jonić, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313669/
https://www.ncbi.nlm.nih.gov/pubmed/37391578
http://dx.doi.org/10.1038/s41598-023-37037-9