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MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations
Cryo electron tomography (cryo-ET) allows observing macromolecular complexes in their native environment. The common routine of subtomogram averaging (STA) allows obtaining the three-dimensional (3D) structure of abundant macromolecular complexes, and can be coupled with discrete classification to r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313669/ https://www.ncbi.nlm.nih.gov/pubmed/37391578 http://dx.doi.org/10.1038/s41598-023-37037-9 |