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Nrh L11R single nucleotide polymorphism, a new prediction biomarker in breast cancer, impacts endoplasmic reticulum-dependent Ca(2+) traffic and response to neoadjuvant chemotherapy

Overexpression of Bcl-2 proteins such as Bcl2L10, also referred to as Nrh, is associated with resistance to therapy and poor survival in various cancers, including breast cancer, lung cancer, and leukemia. The single nucleotide polymorphism (SNP) of BCL2L10 in its BH4 domain at position 11 (BCL2L10...

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Detalles Bibliográficos
Autores principales: Duong, Minh Quang, Gadet, Rudy, Treilleux, Isabelle, Borel, Stéphane, Nougarède, Adrien, Marcillat, Olivier, Gonzalo, Philippe, Mikaelian, Ivan, Popgeorgiev, Nikolay, Rimokh, Ruth, Gillet, Germain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313725/
https://www.ncbi.nlm.nih.gov/pubmed/37391438
http://dx.doi.org/10.1038/s41419-023-05917-7