NADPH oxidase mediated oxidative stress signaling in FLT3-ITD acute myeloid leukemia

The internal tandem duplication of the juxtamembrane domain of the FMS-like tyrosine kinase 3 (FLT3-ITD) is the most common genetic change in acute myeloid leukemia (AML), and about 30% of all AMLs harbor a FLT3-ITD mutation. Even though FLT3 inhibitors have displayed encouraging effects in FLT3-ITD...

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Detalles Bibliográficos
Autores principales: Chen, Yongfeng, Zou, Zhenyou, Găman, Mihnea-Alexandru, Xu, Linglong, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313758/
https://www.ncbi.nlm.nih.gov/pubmed/37391442
http://dx.doi.org/10.1038/s41420-023-01528-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313758/
https://www.ncbi.nlm.nih.gov/pubmed/37391442
http://dx.doi.org/10.1038/s41420-023-01528-5

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