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Differentiation of IL-26(+) T(H)17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis

Interleukin (IL)-26 is a T(H)17 cytokine with known antimicrobial and pro-inflammatory functions. However, the precise role of IL-26 in the context of pathogenic T(H)17 responses is unknown. Here we identify a population of blood T(H)17 intermediates that produce high levels of IL-26 and differentia...

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Detalles Bibliográficos
Autores principales: Fries, Anissa, Saidoune, Fanny, Kuonen, François, Dupanloup, Isabelle, Fournier, Nadine, Guerra de Souza, Ana Cristina, Haniffa, Muzlifah, Ma, Feiyang, Gudjonsson, Johann E., Roesner, Lennart, Li, Yang, Werfel, Thomas, Conrad, Curdin, Gottardo, Raphael, Modlin, Robert L., Di Domizio, Jeremy, Gilliet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313793/
https://www.ncbi.nlm.nih.gov/pubmed/37391412
http://dx.doi.org/10.1038/s41467-023-39484-4