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Lipoxygenase inhibitory synthetic derivatives of methyl gallate regulate gene expressions of COX-2 and cytokines to reduce animal model arthritis

Mammalian lipoxygenases (LOXs) are involved in the biosynthesis of mediators of anaphylactic reactions and have been implicated in cell maturation, the pathogenesis of bronchial asthma, atherosclerosis, rheumatoid arthritis, cardiovascular diseases, Alzheimer’s disease and osteoporosis. Hence LOX in...

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Detalles Bibliográficos
Autores principales: Sharanya, C.S., Abhithaj, J., Arun, K.G., Eeda, Koti Reddy, Bhat, Vignesh, Variyar, E.J., Sabu, A., Haridas, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313808/
https://www.ncbi.nlm.nih.gov/pubmed/37391468
http://dx.doi.org/10.1038/s41598-023-37613-z