Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies

Although anion channel activities have been demonstrated in sarcoplasmic reticulum/endoplasmic reticulum (SR/ER), their molecular identities and functions remain unclear. Here, we link rare variants of Chloride Channel CLIC Like 1 (CLCC1) to amyotrophic lateral sclerosis (ALS)-like pathologies. We d...

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Detalles Bibliográficos
Autores principales: Guo, Liang, Mao, Qionglei, He, Ji, Liu, Xiaoling, Piao, Xuejiao, Luo, Li, Hao, Xiaoxu, Yu, Hanzhi, Song, Qiang, Xiao, Bailong, Fan, Dongsheng, Gao, Zhaobing, Jia, Yichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313822/
https://www.ncbi.nlm.nih.gov/pubmed/37142673
http://dx.doi.org/10.1038/s41422-023-00798-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313822/
https://www.ncbi.nlm.nih.gov/pubmed/37142673
http://dx.doi.org/10.1038/s41422-023-00798-z

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