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MiR-146a-5p deficiency in extracellular vesicles of glioma-associated macrophages promotes epithelial-mesenchymal transition through the NF-κB signaling pathway

Glioma-associated macrophages (GAMs) are pivotal chains in the tumor immune microenvironment (TIME). GAMs mostly display M2-like phenotypes with anti-inflammatory features related to the malignancy and progression of cancers. Extracellular vesicles derived from immunosuppressive GAMs (M2-EVs), the e...

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Detalles Bibliográficos
Autores principales: Xu, Chao, Wang, Pan, Guo, Haiyan, Shao, Chuan, Liao, Bin, Gong, Sheng, Zhou, Yanghao, Yang, Bingjie, Jiang, Haotian, Zhang, Gang, Wu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313823/
https://www.ncbi.nlm.nih.gov/pubmed/37391426
http://dx.doi.org/10.1038/s41420-023-01492-0