Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging

Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed cells with various advanced fluorescence microscopy modalitie...

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Detalles Bibliográficos
Autores principales: Englert, Daniel, Burger, Eva-Maria, Grün, Franziska, Verma, Mrigank S., Lackner, Jens, Lampe, Marko, Bühler, Bastian, Schokolowski, Janin, Nienhaus, G. Ulrich, Jäschke, Andres, Sunbul, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313827/
https://www.ncbi.nlm.nih.gov/pubmed/37391423
http://dx.doi.org/10.1038/s41467-023-39611-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313827/
https://www.ncbi.nlm.nih.gov/pubmed/37391423
http://dx.doi.org/10.1038/s41467-023-39611-1

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