Cargando…

Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging

Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed cells with various advanced fluorescence microscopy modalitie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Englert, Daniel, Burger, Eva-Maria, Grün, Franziska, Verma, Mrigank S., Lackner, Jens, Lampe, Marko, Bühler, Bastian, Schokolowski, Janin, Nienhaus, G. Ulrich, Jäschke, Andres, Sunbul, Murat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313827/ https://www.ncbi.nlm.nih.gov/pubmed/37391423 http://dx.doi.org/10.1038/s41467-023-39611-1

Ejemplares similares

SRB-2: a promiscuous rainbow aptamer for live-cell RNA imaging
por: Sunbul, Murat, et al.
Publicado: (2018)

Dual-colour imaging of RNAs using quencher- and fluorophore-binding aptamers
por: Arora, Ankita, et al.
Publicado: (2015)

A Color‐Shifting Near‐Infrared Fluorescent Aptamer–Fluorophore Module for Live‐Cell RNA Imaging
por: Zhang, Jingye, et al.
Publicado: (2021)

Spirocyclic rhodamine B benzoisothiazole derivative: a multi-stimuli fluorescent switch manifesting ethanol-responsiveness, photo responsiveness, and acidochromism
por: Battula, Himabindu, et al.
Publicado: (2023)

Stable Spirocyclic Meisenheimer Complexes
por: Al-Kaysi, Rabih O., et al.
Publicado: (2008)

Spirocyclic Motifs in Natural Products
por: Chupakhin, Evgeny, et al.
Publicado: (2019)

Photoactivation of silicon rhodamines via a light-induced protonation
por: Frei, Michelle S., et al.
Publicado: (2019)

New Six-Membered pH-Insensitive Rhodamine Spirocycle in Selective Sensing of Cu(2+) through C–C Bond Cleavage and Its Application in Cell Imaging
por: Majumdar, Anupam, et al.
Publicado: (2017)

Energetic Tuning in Spirocyclic Conjugated Polymers
por: Bronstein, Hugo, et al.
Publicado: (2016)

Oxa-spirocycles: synthesis, properties and applications
por: Fominova, Kateryna, et al.
Publicado: (2021)

Spirocyclic derivatives as antioxidants: a review
por: Acosta-Quiroga, Karen, et al.
Publicado: (2021)

Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super‐Resolution STED Microscopy in Living Cells
por: Butkevich, Alexey N., et al.
Publicado: (2016)

Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole
por: Gurry, Michael, et al.
Publicado: (2015)

Scalable Synthesis of Biologically Relevant Spirocyclic Pyrrolidines
por: Melnykov, Kostiantyn P., et al.
Publicado: (2019)

Leishmanicidal Evaluation of Tetrahydroprotoberberine and Spirocyclic Erythrina-Alkaloids
por: Callejon, Daniel R., et al.
Publicado: (2014)

New Methods for the Synthesis of Spirocyclic Cephalosporin Analogues
por: Zhao, Alan X., et al.
Publicado: (2021)

A modular and divergent approach to spirocyclic pyrrolidines
por: Shennan, Benjamin D. A., et al.
Publicado: (2020)

Exploration of Spirocyclic Derivatives of Ciprofloxacin as Antibacterial Agents
por: Lukin, Alexei, et al.
Publicado: (2022)

Synthesis of a Far‐Red Photoactivatable Silicon‐Containing Rhodamine for Super‐Resolution Microscopy
por: Grimm, Jonathan B., et al.
Publicado: (2015)

Shell-Isolated Au Nanoparticles Functionalized with Rhodamine B Fluorophores in Helium Nanodroplets
por: Messner, Roman, et al.
Publicado: (2020)

Synthesis of spirocyclic scaffolds using hypervalent iodine reagents
por: Singh, Fateh V, et al.
Publicado: (2018)

Unnatural spirocyclic oxindole alkaloids biosynthesis in Uncaria guianensis
por: Lopes, Adriana A., et al.
Publicado: (2019)

Synthetic Routes to Approved Drugs Containing a Spirocycle †
por: Moshnenko, Nazar, et al.
Publicado: (2023)

Spirocyclic Nitroxides as Versatile Tools in Modern Natural Sciences: From Synthesis to Applications. Part I. Old and New Synthetic Approaches to Spirocyclic Nitroxyl Radicals
por: Zaytseva, Elena V., et al.
Publicado: (2021)

Recent Progress in Small Spirocyclic, Xanthene-Based Fluorescent Probes
por: G. Keller, Sascha, et al.
Publicado: (2020)

Synthesis and Cytotoxicity Evaluation of Spirocyclic Bromotyrosine Clavatadine C Analogs
por: Patel, Piyush A., et al.
Publicado: (2021)

Synthesis and Characterization of Spirocyclic Mid-Block Containing Triblock Copolymer
por: Aswale, Suraj, et al.
Publicado: (2023)

Modular, automated synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines
por: Cao, Qiao, et al.
Publicado: (2023)

Synthesis and Antibacterial Evaluation of Ciprofloxacin Congeners with Spirocyclic Amine Periphery
por: Lukin, Alexei, et al.
Publicado: (2023)

Synthesis of Dihydropyridine Spirocycles by Semi-Pinacol-Driven Dearomatization of Pyridines
por: Abell, Joseph C., et al.
Publicado: (2023)

Recent Advances in Stereoselective Ring Expansion of Spirocyclopropanes: Access to the Spirocyclic Compounds
por: Sarkar, Tanumay, et al.
Publicado: (2020)

Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives
por: Cihan-Üstündağ, Gökçe, et al.
Publicado: (2019)

Rhodamine 101 Conjugates of Triterpenoic Amides Are of Comparable Cytotoxicity as Their Rhodamine B Analogs
por: Heise, Niels V., et al.
Publicado: (2022)

Using an RNA aptamer probe for super-resolution imaging of native EGFR
por: Yan, Qiuyan, et al.
Publicado: (2018)

Spirocyclic Drimanes from the Marine Fungus Stachybotrys sp. Strain MF347
por: Wu, Bin, et al.
Publicado: (2014)

Synthesis of D-fructose-derived spirocyclic 2-substituted-2-oxazoline ribosides
por: Vangala, Madhuri, et al.
Publicado: (2015)

Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium(iii) ylides
por: Rotstein, Benjamin H., et al.
Publicado: (2016)

Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment‐Based Drug Discovery
por: King, Thomas A., et al.
Publicado: (2019)

Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
por: Venkateshwarlu, Rapolu, et al.
Publicado: (2020)

Visible-light-driven spirocyclization of epoxides via dual titanocene and photoredox catalysis
por: Lin, Shuangjie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7im6belfodej99ciikrm6kjijl