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ssDNA accessibility of Rad51 is regulated by orchestrating multiple RPA dynamics

The eukaryotic single-stranded DNA (ssDNA)-binding protein Replication Protein A (RPA) plays a crucial role in various DNA metabolic pathways, including DNA replication and repair, by dynamically associating with ssDNA. While the binding of a single RPA molecule to ssDNA has been thoroughly studied,...

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Detalles Bibliográficos
Autores principales: Ding, Jiawei, Li, Xiangting, Shen, Jiangchuan, Zhao, Yiling, Zhong, Shuchen, Lai, Luhua, Niu, Hengyao, Qi, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313831/
https://www.ncbi.nlm.nih.gov/pubmed/37391417
http://dx.doi.org/10.1038/s41467-023-39579-y