Testing the “RCT augmentation” methodology: A trial simulation study to guide the broadening of trials eligibility criteria and inform on effectiveness

BACKGROUND: Exclusion criteria that are treatment effect modifiers (TEM) decrease RCTs results generalisability and the potentials of effectiveness estimation. In “augmented RCTs”, a small proportion of otherwise-excluded patients are included to allow for effectiveness estimation. In Hodgkin Lympho...

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Detalles Bibliográficos
Autores principales: Nordon, Clementine, Sanchez, Benoit, Zhang, Mei, Wang, Xiaowei, Hunt, Phillip, Belger, Mark, Karcher, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313858/
https://www.ncbi.nlm.nih.gov/pubmed/37397428
http://dx.doi.org/10.1016/j.conctc.2023.101142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313858/
https://www.ncbi.nlm.nih.gov/pubmed/37397428
http://dx.doi.org/10.1016/j.conctc.2023.101142

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