Alterations of fractional anisotropy throughout cortico-basal ganglia gray matter in a macaque model of Huntington’s Disease

We recently generated a nonhuman primate (NHP) model of the neurodegenerative disorder Huntington's disease (HD) using adeno-associated viral vectors to express a fragment of mutant HTT protein (mHTT) throughout the cortico-basal ganglia circuit. Previous work by our group established that mHTT...

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Detalles Bibliográficos
Autores principales: Weiss, Alison R., Liguore, William A., Brandon, Kristin, Wang, Xiaojie, Liu, Zheng, Kroenke, Christopher D., McBride, Jodi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles from the special issue: Illuminating the Monkey Brain: Organization, Networks and Circuits, edited by Yogita Chudasama and Xiaoqin Wang
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313883/
https://www.ncbi.nlm.nih.gov/pubmed/37397804
http://dx.doi.org/10.1016/j.crneur.2023.100090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313883/
https://www.ncbi.nlm.nih.gov/pubmed/37397804
http://dx.doi.org/10.1016/j.crneur.2023.100090

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