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Alterations of fractional anisotropy throughout cortico-basal ganglia gray matter in a macaque model of Huntington’s Disease
We recently generated a nonhuman primate (NHP) model of the neurodegenerative disorder Huntington's disease (HD) using adeno-associated viral vectors to express a fragment of mutant HTT protein (mHTT) throughout the cortico-basal ganglia circuit. Previous work by our group established that mHTT...
Autores principales: | Weiss, Alison R., Liguore, William A., Brandon, Kristin, Wang, Xiaojie, Liu, Zheng, Kroenke, Christopher D., McBride, Jodi L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313883/ https://www.ncbi.nlm.nih.gov/pubmed/37397804 http://dx.doi.org/10.1016/j.crneur.2023.100090 |
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