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Chronic myeloid leukemia kinase domain mutations: A retrospective descriptive study on the therapeutic and prognostic significance in patients at King Edward VIII Hospital, KwaZulu‐Natal, South Africa

BACKGROUND: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm that harbors the Philadelphia chromosome. Tyrosine kinase inhibitor (TKI) therapy has dramatically improved the survival of patients with CML. Nevertheless, 20%–40% of CML patients require changes in TKI therapy due to intol...

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Detalles Bibliográficos
Autores principales: Benjamin, Caryn, Murugan, Stephanie, Hoosen, Siddeeq, Rapiti, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313909/
https://www.ncbi.nlm.nih.gov/pubmed/37396560
http://dx.doi.org/10.1002/hsr2.1376