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A living ex vivo platform for functional, personalized brain cancer diagnosis

Functional precision medicine platforms are emerging as promising strategies to improve pre-clinical drug testing and guide clinical decisions. We have developed an organotypic brain slice culture (OBSC)-based platform and multi-parametric algorithm that enable rapid engraftment, treatment, and anal...

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Detalles Bibliográficos
Autores principales: Mann, Breanna, Zhang, Xiaopei, Bell, Noah, Adefolaju, Adebimpe, Thang, Morrent, Dasari, Rajaneekar, Kanchi, Krishna, Valdivia, Alain, Yang, Yang, Buckley, Andrew, Lettry, Vivien, Quinsey, Carolyn, Rauf, Yasmeen, Kram, David, Cassidy, Noah, Vaziri, Cyrus, Corcoran, David L., Rego, Stephen, Jiang, Yuchao, Graves, Lee M., Dunn, Denise, Floyd, Scott, Baldwin, Albert, Hingtgen, Shawn, Satterlee, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313921/
https://www.ncbi.nlm.nih.gov/pubmed/37192626
http://dx.doi.org/10.1016/j.xcrm.2023.101042