Randomised phase 2 study (JADE) of the HBV capsid assembly modulator JNJ-56136379 with or without a nucleos(t)ide analogue in patients with chronic hepatitis B infection

OBJECTIVE: We present the final analysis results of the phase 2 JADE study (ClinicalTrials.gov Identifier: NCT03361956). DESIGN: 232 patients with chronic hepatitis B (CHB) not currently treated at study start (NCT) at study start or virologically suppressed were randomised to receive 75 mg (part 1)...

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Detalles Bibliográficos
Autores principales: Janssen, Harry L A, Hou, Jinlin, Asselah, Tarik, Chan, Henry L Y, Zoulim, Fabien, Tanaka, Yasuhito, Janczewska, Ewa, Nahass, Ronald G, Bourgeois, Stefan, Buti, Maria, Lampertico, Pietro, Lenz, Oliver, Verbinnen, Thierry, Vandenbossche, Joris, Talloen, Willem, Kalmeijer, Ronald, Beumont, Maria, Biermer, Michael, Shukla, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313999/
https://www.ncbi.nlm.nih.gov/pubmed/36697207
http://dx.doi.org/10.1136/gutjnl-2022-328041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10313999/
https://www.ncbi.nlm.nih.gov/pubmed/36697207
http://dx.doi.org/10.1136/gutjnl-2022-328041

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