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Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance

OBJECTIVES: Little is known about the immunology underlying variable treatment response in rheumatoid arthritis (RA). We performed large-scale transcriptome analyses of peripheral blood immune cell subsets to identify immune cells that predict treatment resistance. METHODS: We isolated 18 peripheral...

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Detalles Bibliográficos
Autores principales: Yamada, Saeko, Nagafuchi, Yasuo, Wang, Min, Ota, Mineto, Hatano, Hiroaki, Takeshima, Yusuke, Okubo, Mai, Kobayashi, Satomi, Sugimori, Yusuke, Masahiro, Nakano, Yoshida, Ryochi, Hanata, Norio, Suwa, Yuichi, Tsuchida, Yumi, Iwasaki, Yukiko, Sumitomo, Shuji, Kubo, Kanae, Shimane, Kenichi, Setoguchi, Keigo, Azuma, Takanori, Kanda, Hiroko, Shoda, Hirofumi, Zhang, Xuan, Yamamoto, Kazuhiko, Ishigaki, Kazuyoshi, Okamura, Tomohisa, Fujio, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314026/
https://www.ncbi.nlm.nih.gov/pubmed/36918189
http://dx.doi.org/10.1136/ard-2022-223645