Prognostic biomarkers in prodromal α-synucleinopathies: DAT binding and REM sleep without atonia

BACKGROUND: Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is a prodromal state of clinical α-synucleinopathies such as Parkinson’s disease and Lewy body dementia. The lead-time until conversion is unknown. The most reliable marker of progression is reduced striatal dopamine trans...

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Detalles Bibliográficos
Autores principales: Kunz, Dieter, Stotz, Sophia, de Zeeuw, Jan, Papakonstantinou, Alexandra, Dümchen, Susanne, Haberecht, Martin, Plotkin, Michail, Bes, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314035/
https://www.ncbi.nlm.nih.gov/pubmed/36725328
http://dx.doi.org/10.1136/jnnp-2022-330048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314035/
https://www.ncbi.nlm.nih.gov/pubmed/36725328
http://dx.doi.org/10.1136/jnnp-2022-330048

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