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Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis

RATIONALE: A better understanding of the mechanism of action of mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) is needed to support their use as novel therapies for acute respiratory distress syndrome (ARDS). Macrophages are important mediators of ARDS inflammatory response....

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Detalles Bibliográficos
Autores principales: Su, Yue, Silva, Johnatas Dutra, Doherty, Declan, Simpson, David A, Weiss, Daniel J, Rolandsson-Enes, Sara, McAuley, Daniel F, O'Kane, Cecilia M, Brazil, Derek P, Krasnodembskaya, Anna D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314068/
https://www.ncbi.nlm.nih.gov/pubmed/35948417
http://dx.doi.org/10.1136/thoraxjnl-2021-218194