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Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis
RATIONALE: A better understanding of the mechanism of action of mesenchymal stromal cells (MSCs) and their extracellular vesicles (EVs) is needed to support their use as novel therapies for acute respiratory distress syndrome (ARDS). Macrophages are important mediators of ARDS inflammatory response....
Autores principales: | Su, Yue, Silva, Johnatas Dutra, Doherty, Declan, Simpson, David A, Weiss, Daniel J, Rolandsson-Enes, Sara, McAuley, Daniel F, O'Kane, Cecilia M, Brazil, Derek P, Krasnodembskaya, Anna D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314068/ https://www.ncbi.nlm.nih.gov/pubmed/35948417 http://dx.doi.org/10.1136/thoraxjnl-2021-218194 |
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