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Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis

OBJECTIVE: In acute pancreatitis (AP), bacterial translocation and subsequent infection of pancreatic necrosis are the main risk factors for severe disease and late death. Understanding how immunological host defence mechanisms fail to protect the intestinal barrier is of great importance in reducin...

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Detalles Bibliográficos
Autores principales: Glaubitz, Juliane, Wilden, Anika, Frost, Fabian, Ameling, Sabine, Homuth, Georg, Mazloum, Hala, Rühlemann, Malte Christoph, Bang, Corinna, Aghdassi, Ali A, Budde, Christoph, Pickartz, Tilmann, Franke, Andre, Bröker, Barbara M, Voelker, Uwe, Mayerle, Julia, Lerch, Markus M, Weiss, Frank-Ulrich, Sendler, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314084/
https://www.ncbi.nlm.nih.gov/pubmed/36631247
http://dx.doi.org/10.1136/gutjnl-2022-327448