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Microbial lipopolysaccharide‐induced inflammation contributes to cognitive impairment and white matter lesion progression in diet‐induced obese mice with chronic cerebral hypoperfusion

AIMS: White matter lesions (WMLs) are involved in the pathological processes leading to cognitive decline and dementia. We examined the mechanisms underlying the exacerbation of ischemia‐induced cognitive impairment and WMLs by diet‐induced obesity, including lipopolysaccharide (LPS)‐triggered neuro...

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Detalles Bibliográficos
Autores principales: Inaba, Toshiki, Yamashiro, Kazuo, Kurita, Naohide, Ueno, Yuji, Miyamoto, Nobukazu, Hira, Kenichiro, Nakajima, Sho, Kijima, Chikage, Nakaguro, Ryohei, Urabe, Takao, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314110/
https://www.ncbi.nlm.nih.gov/pubmed/37287396
http://dx.doi.org/10.1111/cns.14301