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Efficacy and safety of a self-applied carrageenan-based gel to prevent human papillomavirus infection in sexually active young women (CATCH study): an exploratory phase IIB randomised, placebo-controlled trial

BACKGROUND: Carrageenan demonstrated potent anti-HPV (human papillomavirus) activity in vitro and in animal models. The Carrageenan-gel Against Transmission of Cervical Human papillomavirus trial’s interim analysis (n = 277) demonstrated a 36% protective effect of carrageenan against incident HPV in...

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Detalles Bibliográficos
Autores principales: Laurie, Cassandra, El-Zein, Mariam, Botting-Provost, Sarah, Tota, Joseph E., Tellier, Pierre-Paul, Coutlée, François, Burchell, Ann N., Franco, Eduardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314142/
https://www.ncbi.nlm.nih.gov/pubmed/37396806
http://dx.doi.org/10.1016/j.eclinm.2023.102038