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Efficacy and safety of topically applied therapeutic ammonia oxidising bacteria in adults with mild-to-moderate atopic dermatitis and moderate-to-severe pruritus: a randomised, double-blind, placebo-controlled, dose-ranging, phase 2b trial

BACKGROUND: Topical anti-inflammatory therapy is a cornerstone of treatment for atopic dermatitis (AD). However, many unmet needs remain with existing therapies. B244 is a live topical biotherapeutic being tested for the reduction of pruritus and improvement of eczema signs in patients with AD. We a...

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Detalles Bibliográficos
Autores principales: Silverberg, Jonathan I., Lio, Peter A., Simpson, Eric L., Li, Connie, Brownell, Daniel R., Gryllos, Ioannis, Ng-Cashin, Judith, Krueger, Todd, Swaidan, Victoria R., Bliss, Robin L., Kim, Hyun D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314159/
https://www.ncbi.nlm.nih.gov/pubmed/37396805
http://dx.doi.org/10.1016/j.eclinm.2023.102002