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Efficacy and safety of topically applied therapeutic ammonia oxidising bacteria in adults with mild-to-moderate atopic dermatitis and moderate-to-severe pruritus: a randomised, double-blind, placebo-controlled, dose-ranging, phase 2b trial
BACKGROUND: Topical anti-inflammatory therapy is a cornerstone of treatment for atopic dermatitis (AD). However, many unmet needs remain with existing therapies. B244 is a live topical biotherapeutic being tested for the reduction of pruritus and improvement of eczema signs in patients with AD. We a...
Autores principales: | Silverberg, Jonathan I., Lio, Peter A., Simpson, Eric L., Li, Connie, Brownell, Daniel R., Gryllos, Ioannis, Ng-Cashin, Judith, Krueger, Todd, Swaidan, Victoria R., Bliss, Robin L., Kim, Hyun D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314159/ https://www.ncbi.nlm.nih.gov/pubmed/37396805 http://dx.doi.org/10.1016/j.eclinm.2023.102002 |
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