The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs

This study aimed at developing the Diamod® as a dynamic gastrointestinal transfer model with physically interconnected permeation. The Diamod® was validated by studying the impact of the intraluminal dilution of a cyclodextrin-based itraconazole solution and the negative food effect for indinavir su...

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Detalles Bibliográficos
Autores principales: Moens, Frédéric, Vandevijver, Gies, De Blaiser, Anke, Larsson, Adam, Spreafico, Fabio, Augustijns, Patrick, Marzorati, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Special Issue on Interreg project “Site-Specific Drug Delivery”
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314207/
https://www.ncbi.nlm.nih.gov/pubmed/37396621
http://dx.doi.org/10.1016/j.ijpx.2023.100177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314207/
https://www.ncbi.nlm.nih.gov/pubmed/37396621
http://dx.doi.org/10.1016/j.ijpx.2023.100177

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