CircTBX5 knockdown modulates the miR-558/MyD88 axis to alleviate IL-1β-induced inflammation, apoptosis and extracellular matrix degradation in chondrocytes via inactivating the NF-κB signaling

BACKGROUND: It has been widely shared that the dysregulation of circular RNA (circRNA) may contribute to the progression of osteoarthritis (OA). OA is characterized by persistent chondrocyte injury. We aimed to clarify the role of circTBX5 in IL-1β-induced chondrocyte injury. METHODS: The expression...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Mu, Hongjie, Cui, Qiaoyi, Yu, Peng, Liu, Tong, Wang, Tao, Sheng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314403/
https://www.ncbi.nlm.nih.gov/pubmed/37393232
http://dx.doi.org/10.1186/s13018-023-03949-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314403/
https://www.ncbi.nlm.nih.gov/pubmed/37393232
http://dx.doi.org/10.1186/s13018-023-03949-5

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