Endothelial progenitor cell-derived exosomes promote anti-inflammatory macrophages via SOCS3/JAK2/STAT3 axis and improve the outcome of spinal cord injury

BACKGROUND: Macrophage in the spinal cord injury (SCI) area imparts a chronic pro-inflammation effect that challenges the recovery of SCI. Previously, endothelial progenitor cell-produced exosomes (EPC-EXOs) have been noticed to facilitate revascularization and inflammation control after SCI. Howeve...

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Detalles Bibliográficos
Autores principales: Yuan, Feifei, Peng, Wei, Yang, Yuying, Xu, Jiaqi, Liu, Yudong, Xie, Yong, Huang, Tingmo, Shi, Chaoran, Ding, Yinghe, Li, Chengjun, Qin, Tian, Xie, Shanshan, Zhu, Fengzhang, Lu, Hongbin, Huang, Jianjun, Hu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314438/
https://www.ncbi.nlm.nih.gov/pubmed/37391774
http://dx.doi.org/10.1186/s12974-023-02833-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314438/
https://www.ncbi.nlm.nih.gov/pubmed/37391774
http://dx.doi.org/10.1186/s12974-023-02833-7

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