Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy

BACKGROUND: Aside from immune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1), intervention of CD47/Sirpα mediated ‘don’t eat me’ signal between macrophage and tumor cell is considered as a promising therapeutic approach for cancer immunot...

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Detalles Bibliográficos
Autores principales: Shen, Wenhui, Shi, Peishang, Dong, Qingyu, Zhou, Xiuman, Chen, Chunxia, Sui, Xinghua, Tian, Wentong, Zhu, Xueqin, Wang, Xiaoxi, Jin, Shengzhe, Wu, Yahong, Chen, Guanyu, Qiu, Lu, Zhai, Wenjie, Gao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314633/
https://www.ncbi.nlm.nih.gov/pubmed/37344099
http://dx.doi.org/10.1136/jitc-2023-007068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314633/
https://www.ncbi.nlm.nih.gov/pubmed/37344099
http://dx.doi.org/10.1136/jitc-2023-007068

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