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Anticitrullinated peptide antibody epitope expansion and the HLA DRB1 ‘shared epitope’ are less common in seropositive checkpoint inhibitor-induced inflammatory arthritis than in longstanding rheumatoid arthritis

BACKGROUND: Immune checkpoint inhibitors (ICI) can potentially cause ICI-inflammatory arthritis (ICI-IA), which often resembles rheumatoid arthritis (RA). In this study, we examined the degree of anticitrullinated peptide antibodies (ACPA) epitope expansion in CCP+ICI-IA and patients with RA. METHOD...

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Detalles Bibliográficos
Autores principales: Ghosh, Nilasha, Reid, Pankti, Aude, Carlos Andres, Kirschman, Jessica, Goodman, Susan, Bykerk, Vivian P, Lakhanpal, Amit, Rajesh, Diviya, Chan, Karmela K, Robinson, William H, Bass, Anne R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314674/
https://www.ncbi.nlm.nih.gov/pubmed/37355249
http://dx.doi.org/10.1136/rmdopen-2023-003012