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circ-0000512 inhibits PD-L1 ubiquitination through sponging miR-622/CMTM6 axis to promote triple-negative breast cancer and immune escape

BACKGROUND: This study reported the function and mechanism of circ-0000512 in the progression of triple-negative breast cancer (TNBC). METHODS: circ-0000512 expression in TNBC tissues and paired adjacent normal tissues and cells was examined by qRT-PCR. Moreover, circ-0000512 expression in TNBC cell...

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Detalles Bibliográficos
Autores principales: Dong, Li-Feng, Chen, Fang-Fang, Fan, Yang-Fan, Zhang, Kun, Chen, Hui-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314703/
https://www.ncbi.nlm.nih.gov/pubmed/37349124
http://dx.doi.org/10.1136/jitc-2022-005461