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Concurrent immune checkpoint inhibition and selective immunosuppressive therapy in patients with immune-related enterocolitis

PURPOSE: Immune checkpoint inhibitor (ICI) therapy is often suspended because of immune-related enterocolitis (irEC). We examined the effect of resumption of ICIs with or without concurrent selective immunosuppressive therapy (SIT) on rates of symptom recurrence and survival outcomes. METHODS: This...

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Detalles Bibliográficos
Autores principales: Badran, Yousef R, Zou, Fangwen, Durbin, Sienna M, Dutra, Barbara E, Abu-Sbeih, Hamzah, Thomas, Anusha S, Altan, Mehmet, Thompson, John A, Qiao, Wei, Leet, Donna E, Lai, Po-Ying, Horick, Nora K, Postow, Michael A, Faleck, David M, Wang, Yinghong, Dougan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314704/
https://www.ncbi.nlm.nih.gov/pubmed/37349130
http://dx.doi.org/10.1136/jitc-2023-007195