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Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus

PURPOSE: The study aimed to determine the expression of VISTA and TOX within venous tumor thrombus and primary clear cell renal cell carcinoma (ccRCC) and to assess their prognostic value. METHODS: The study enrolled 82 patients with ccRCC and coexisting venous tumor thrombus treated radically from...

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Detalles Bibliográficos
Autores principales: Zapała, Łukasz, Kunc, Michał, Sharma, Sumit, Pęksa, Rafał, Popęda, Marta, Biernat, Wojciech, Radziszewski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314835/
https://www.ncbi.nlm.nih.gov/pubmed/36042047
http://dx.doi.org/10.1007/s00432-022-04329-y