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The expression of the adenosine pathway markers CD39 and CD73 in salivary gland carcinomas harbors the potential for novel immune checkpoint inhibition

BACKGROUND: In salivary gland carcinomas (SGC), there is only a small fraction of entities that appears to profit from immune checkpoint inhibition (ICI). Recent findings connected the activation of adenosine-signaling with a tolerogenic microenvironment. Therefore, the inhibition of adenosine pathw...

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Detalles Bibliográficos
Autores principales: Bauer, Arthur, Gebauer, Niklas, Knief, Juliana, Tharun, Lars, Arnold, Nele, Riecke, Armin, Steinestel, Konrad, Witte, Hanno M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314850/
https://www.ncbi.nlm.nih.gov/pubmed/35902382
http://dx.doi.org/10.1007/s00432-022-04211-x