The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj(−/−) mice

Apolipoprotein J (APOJ) is a multifunctional protein with genetic evidence suggesting an association between APOJ polymorphisms and Alzheimer’s disease as well as exfoliation glaucoma. Herein we conducted ocular characterizations of Apoj(−/−) mice and found that their retinal cholesterol levels were...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Darzi, Nicole, Mast, Natalia, Li, Yong, Dailey, Brian, Kang, Min, Rhee, Douglas J., Pikuleva, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314885/
https://www.ncbi.nlm.nih.gov/pubmed/37392222
http://dx.doi.org/10.1007/s00018-023-04848-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314885/
https://www.ncbi.nlm.nih.gov/pubmed/37392222
http://dx.doi.org/10.1007/s00018-023-04848-y

Ejemplares similares