Transient receptor potential ankyrin 1 (TRPA1) mediates reactive oxygen species-induced Ca(2+) entry, mitochondrial dysfunction, and caspase-3/7 activation in primary cultures of metastatic colorectal carcinoma cells

Colorectal carcinoma (CRC) represents the fourth most common cancer worldwide and is the third most common cause of malignancy-associated mortality. Distant metastases to the liver and lungs are the main drivers of CRC-dependent death. Pro-oxidant therapies, which halt disease progression by exacerb...

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Detalles Bibliográficos
Autores principales: Faris, Pawan, Rumolo, Agnese, Pellavio, Giorgia, Tanzi, Matteo, Vismara, Mauro, Berra-Romani, Roberto, Gerbino, Andrea, Corallo, Salvatore, Pedrazzoli, Paolo, Laforenza, Umberto, Montagna, Daniela, Moccia, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314907/
https://www.ncbi.nlm.nih.gov/pubmed/37393347
http://dx.doi.org/10.1038/s41420-023-01530-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314907/
https://www.ncbi.nlm.nih.gov/pubmed/37393347
http://dx.doi.org/10.1038/s41420-023-01530-x

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