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Tim-3 protects against cisplatin nephrotoxicity by inhibiting NF-κB-mediated inflammation

The impact of Tim-3 (T cell immunoglobulin and mucin domain-containing protein 3) on cisplatin-induced acute kidney injury was investigated in this study. Cisplatin-induced Tim-3 expression in mice kidney tissues and proximal tubule-derived BUMPT cells in a time-dependent manner. Compared with wild-...

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Detalles Bibliográficos
Autores principales: Li, Peiyao, Li, Xuemiao, Wu, Wenbin, Hou, Mengjia, Yin, Guanyi, Wang, Zhonghang, Du, Ziyu, Ma, Yuanfang, Lou, Qiang, Wei, Yinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314935/
https://www.ncbi.nlm.nih.gov/pubmed/37393392
http://dx.doi.org/10.1038/s41420-023-01519-6