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Molecular characteristics of microsatellite stable early-onset colorectal cancer as predictors of prognosis and immunotherapeutic response

The incidence of early-onset colorectal cancer (EO-CRC, in patients younger than 50) is increasing worldwide. The specific gene signatures in EO-CRC patients are largely unknown. Since EO-CRC with microsatellite instability is frequently associated with Lynch syndrome, we aimed to comprehensively ch...

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Detalles Bibliográficos
Autores principales: Lu, Can, Zhang, Xiaopeng, Schardey, Josefine, Wirth, Ulrich, Heinrich, Kathrin, Massiminio, Luca, Cavestro, Giulia Martina, Neumann, Jens, Bazhin, Alexandr V., Werner, Jens, Kühn, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314951/
https://www.ncbi.nlm.nih.gov/pubmed/37393364
http://dx.doi.org/10.1038/s41698-023-00414-8