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Regulation of Macrophage Cell Surface GAPDH Alters LL-37 Internalization and Downstream Effects in the Cell

Mycobacterium tuberculosis (M.tb), the major causative agent of tuberculosis, has evolved mechanisms to evade host defenses and persist within host cells. Host-directed therapies against infected cells are emerging as an effective option. Cationic host defense peptide LL-37 is known to internalize i...

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Detalles Bibliográficos
Autores principales: Dhiman, Asmita, Talukdar, Sharmila, Chaubey, Gaurav Kumar, Dilawari, Rahul, Modanwal, Radheshyam, Chaudhary, Surbhi, Patidar, Anil, Boradia, Vishant Mahendra, Kumbhar, Pradeep, Raje, Chaaya Iyengar, Raje, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315065/
https://www.ncbi.nlm.nih.gov/pubmed/37080180
http://dx.doi.org/10.1159/000530083