Effect of FTY-720 on Pulmonary Fibrosis in Mice via the TGF-β1 Signaling Pathway and Autophagy

We investigated whether FTY-720 might have an effect on bleomycin-induced pulmonary fibrosis through inhibiting TGF-β1 pathway, and up-regulating autophagy. The pulmonary fibrosis was induced by bleomycin. FTY-720 (1 mg/kg) drug was intraperitoneally injected into mice. Histological changes and infl...

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Detalles Bibliográficos
Autores principales: Jin, Yuying, Liu, Weidong, Gao, Ge, Song, Yilan, Liu, Hanye, Li, Liangchang, Zhou, Jiaxu, Yan, Guanghai, Cui, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315338/
https://www.ncbi.nlm.nih.gov/pubmed/37019836
http://dx.doi.org/10.4062/biomolther.2022.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315338/
https://www.ncbi.nlm.nih.gov/pubmed/37019836
http://dx.doi.org/10.4062/biomolther.2022.123

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