5-Hydroxytryptophan Reduces Levodopa-Induced Dyskinesia via Regulating AKT/mTOR/S6K and CREB/ΔFosB Signals in a Mouse Model of Parkinson’s Disease

Long-term administration of levodopa (L-DOPA) to patients with Parkinson’s disease (PD) commonly results in involuntary dyskinetic movements, as is known for L-DOPA-induced dyskinesia (LID). 5-Hydroxytryptophan (5-HTP) has recently been shown to alleviate LID; however, no biochemical alterations to...

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Detalles Bibliográficos
Autores principales: Choi, Yujin, Huh, Eugene, Lee, Seungmin, Kim, Jin Hee, Park, Myoung Gyu, Seo, Seung-Yong, Kim, Sun Yeou, Oh, Myung Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315339/
https://www.ncbi.nlm.nih.gov/pubmed/36918741
http://dx.doi.org/10.4062/biomolther.2022.141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315339/
https://www.ncbi.nlm.nih.gov/pubmed/36918741
http://dx.doi.org/10.4062/biomolther.2022.141

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