3-Deoxysappanchalcone Inhibits Cell Growth of Gefitinib-Resistant Lung Cancer Cells by Simultaneous Targeting of EGFR and MET Kinases

The mechanistic functions of 3-deoxysappanchalcone (3-DSC), a chalcone compound known to have many pharmacological effects on lung cancer, have not yet been elucidated. In this study, we identified the comprehensive anti-cancer mechanism of 3-DSC, which targets EGFR and MET kinase in drug-resistant...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Young, Lee, Seung-On, Kwak, Ah-Won, Chae, Seon-Bin, Cho, Seung-Sik, Yoon, Goo, Kim, Ki-Taek, Choi, Yung Hyun, Lee, Mee-Hyun, Joo, Sang Hoon, Park, Jin Woo, Shim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315347/
https://www.ncbi.nlm.nih.gov/pubmed/37188656
http://dx.doi.org/10.4062/biomolther.2023.070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315347/
https://www.ncbi.nlm.nih.gov/pubmed/37188656
http://dx.doi.org/10.4062/biomolther.2023.070

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