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Rapidly dissolving bilayer microneedles enabling minimally invasive and efficient protein delivery to the posterior segment of the eye

The discovery of proteins that neutralise vascular endothelial growth factors, such as pegaptanib, ranibizumab and aflibercept, can inhibit the process of angiogenesis, thereby restoring eyesight in individuals with retinal vascular disorders. However, due to the posterior location and chronic natur...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Vora, Lalitkumar K., Donnelly, Ryan F., Singh, Thakur Raghu Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315354/
https://www.ncbi.nlm.nih.gov/pubmed/35713782
http://dx.doi.org/10.1007/s13346-022-01190-x