NBCe1-B/C-knockout mice exhibit an impaired respiratory response and an enhanced renal response to metabolic acidosis

The sodium-bicarbonate cotransporter (NBCe1) has three primary variants: NBCe1-A, -B and -C. NBCe1-A is expressed in renal proximal tubules in the cortical labyrinth, where it is essential for reclaiming filtered bicarbonate, such that NBCe1-A knockout mice are congenitally acidemic. NBCe1-B and -C...

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Detalles Bibliográficos
Autores principales: Brady, Clayton T., Marshall, Aniko, Zhang, Chen, Parker, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315466/
https://www.ncbi.nlm.nih.gov/pubmed/37405134
http://dx.doi.org/10.3389/fphys.2023.1201034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315466/
https://www.ncbi.nlm.nih.gov/pubmed/37405134
http://dx.doi.org/10.3389/fphys.2023.1201034

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