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Pentosan polysulfate sodium promotes redifferentiation to the original phenotype in micromass-cultured canine articular chondrocytes and exerts molecular weight-dependent effects

Pentosan polysulfate sodium (PPS) is a heparin-like polysaccharide that is applied as a therapeutic treatment for osteoarthritis (OA) in animals. This study investigated the efficacy of different molecular weights PPS (1,500–7,000 Da) on the phenotype regulatory and chondrogenic properties of canine...

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Detalles Bibliográficos
Autores principales: WANG, Yanlin, SUNAGA, Takafumi, MWALE, Carol, AKARAPHUTIPORN, Ekkapol, KIM, Sangho, OKUMURA, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315557/
https://www.ncbi.nlm.nih.gov/pubmed/37150611
http://dx.doi.org/10.1292/jvms.22-0567