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Identification of a novel PARP4 gene promoter CpG locus associated with cisplatin chemoresistance

The protein family of poly (ADP-ribose) polymerases (PARPs) is comprised of multifunctional nuclear enzymes. Several PARP inhibitors have been developed as new anticancer drugs to combat resistance to chemotherapy. Herein, we characterized PARP4 mRNA expression profiles in cisplatin-sensitive and ci...

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Detalles Bibliográficos
Autores principales: Sung, Hye Youn, Han, Jihye, Chae, Yun Ju, Ju, Woong, Kang, Jihee Lee, Park, Ae Kyung, Ahn, Jung-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10315564/
https://www.ncbi.nlm.nih.gov/pubmed/37013346
http://dx.doi.org/10.5483/BMBRep.2022-0202